The San Francisco Medical Examiner-Coroner's Office will maintain a Pathological Coordinating Laboratory (PCL) from September 30, 1978 - September 29, 1979. Tissue specimens and autopsy reports from 750 infant death cases will be submitted to the PCL. The tissues will be trimmed fruther by a board-certified forensic pathologist and microscopic slides prepared (30 per case). The slides and corresponding autopsy reports will be sent on a rotational basis to three consulting pathologists for interpretation and diagnosis. Autopsy reports, slide sets and pathologists' diagnostic summaries will be sent to the Data Cooordinating Center at the University of Washington for archiving.